
Welcome to EndometriosisTests.com
Endotest
What is Endotest?
Endotest is a new, highly accurate, non-invasive test for endometriosis.
How is it done?
It involves collecting saliva (spit) in a tube, and then this is tested in a laboratory.
Where is the test done?
The test is performed in the comfort of your own home, and sent to a laboratory for testing. The test is organised through The Doctors Laboratory (TDL) in London, but actually processed in the Ziwig laboratory in France.
What does the result tell you?
The result is either positive (endometriosis is highly likely) or negative (endometriosis is highly unlikely).
How accurate is the test?
Research has shown that the test is very accurate (97%). If the test is positive, there is a 98% chance that if a laparoscopy was done endometriosis wouled be found. If it is negative, there will be no endometriosis in more than 91% of patients.
How does it work?
It tests for a specific microRNA “signature” in the saliva. MicroRNA are molecules involved in the regulation of creation or destruction of proteins in the body. Research suggests that if this process is faulty it can cause endometriosis.
Where can I find out more information about Endotest including research evidence?
https://ziwig.com/en/discover-ziwig-endotest/

How the service works
Simple service from the comfort of your own home
NB The service is currently only available in the U.K.
Order the test
The test has to be requested by a doctor, so we need you to complete a registration with us and a very short form. You will be contacted shortly afterwards by The Doctors Laboratory (TDL) to take payment.
Sample collection
The testing kit will be sent out to you by TDL with simple instructions so you can perform it at home. You then return it to them in the post.
Results
The laboratory aim to return the results to us within three weeks. When we receive them you will be invited to make a results appointment. This will conducted via a video call.
Cost
How much does it cost?
The total cost of this service is £850.
What does the cost include?
The cost includes the required request for the test by a medical professional, the test itself and a results appointment.
Why is the test so expensive?
The equipment and processing required to do this advanced kind of testing is extremely expensive.
Is the test available on the NHS?
Other than one small trial, as far as we are aware, the test is not currently available on the NHS.
Will my health insurance pay for the test?
Some health insurance companies are now covering the test, so if you are insured you may wish to discuss this with them.
Common Questions
Find answers to frequently asked questions about our Endotest service.
What is endometriosis?
Endometriosis is a condition in which cells similar to those that line the inside of the womb (the endometrium) grow outside of the womb. These respond to the hormones of the menstrual cycle in the same way as the endometrium by growing and bleeding. This can cause a host of problems including pain, scarring and difficulties falling pregnant. For further information we would recommend the websites of The Endometriosis Foundation (www.theendometriosisfoundation.org) or Endometriosis UK (www.endometriosis-UK.org).
Is the service confidential?
Absolutely. We prioritize your privacy and ensure that all test results and personal information are kept secure and confidential at all times. Please see our privacy notice for more information.
What will happen at my results appointment?
The 10 minute results appointment will be performed remotely via a video call. It will be conducted by Mr O’Donovan, who will communicate teh .the result to you, explain what it means, answer your questions and help you make a plan for where to go for further advice next. It is not a treatment appointment, i.e. no treatment will be instigated at that appointment. For regulatory reasons we cannot give medical advice at this appointment, but will be more than happy to suggest the best ways to get this. You will receive a short letter explaining the result.
Who is Mr O'Donovan?
He is a gynaecologist and endometriosis specialist. He has been the lead clinician for the Endometriosis Centre at University Hospitals Bristol and Western since 2018. He has huge experience in both the diagnosis and treatment of endometriosis, and currently sits on both the diagnostics and endometriosis centres subcommittees at The British Society for Gynaecological Endoscopy. He is a founding trustee of The Endometriosis Foundation (www.theendometriosisfoundation.org).
Is this test instead of a laparoscopy (keyhole surgery)?
The “gold standard” (most accurate) test to diagnose endometriosis is a laparoscopy. This is key hole surgery, where the surgeon looks inside the abdomen (tummy) with a small camera. It requires a general anaesthetic and, as with any surgery, comes with some risk, pain and inconvenience (most people will require a couple of weeks off work for example).
In the past, if scans have been normal and further investigation were required, that would have been with a laparoscopy. With Endotest, if the result is negative then a laparoscopy to look for endometriosis is not usually required. If Endotest is positive, then we know endometriosis is highly likely to be present and a laparoscopy is not required to determine this. A laparoscopy may still be appropriate for treatment, and knowing that endometriosis will be found helps plan the operation (e.g. which surgeons should be present, how long to allow, more information about risks, recovery times etc). Overall, for many people, Endotest will either avoid the need for laparoscopy or help plan the appropriate surgery.
Does Endotest test for adenomyosis?
No it does not. Adenomyosis is best diagnosed with a scan.
Do you need to stop any medications before doing the Endotest?
No, the test is still accurate whilst on treatments, including pain killers, progesterone only pills, combined pills, hormone containing coils or other hormones.
Does Endotest need to be done at a particular time of the menstrual cycle?
No, it can be done at any time of the cycle.
Is there anyone who can't have the test?
The test can be performed in most people between the ages of 18 and 43. The research has not yet been done outside this age group. There is a study underway currently to see if the test works in those under 18. It also cannot be done in people who are pregnant, have a history of cancer or are HIV positive.
Can I do the test if I am ill?
The test may be inaccurate if you have an infection (e.g. a cold), so you should wait for complete recovery before doing the test.
What if i already have a diagnosis of endometriosis?
If you have already had a diagnosis of endometriosis confirmed, either at laparoscopy or on scan, there is no need to have the test. It will not give you any further information.
What if if the test is negative?
If the test is negative we can be more than 90% certain the person doesn't not have endometriosis. This absolutely does not mean that they do not have symptoms though, and focus can be concentrated on other possible causes.
What if if the test is positive?
If the test is positive the person almost certainly has endometriosis. The test does not tell us about the extent or location of the disease, but informs a plan for treatment and perhaps further investigation.
Proceed with test
Simply click below, this will enable you to register for the test. No payment is required at this point.


